samedan logo
 
 
 
spacer
home > pmps > summer 2007 > the therapeutics of injections
PUBLICATIONS
Pharmaceutical Manufacturing and Packing Sourcer

The Therapeutics of Injections

Kevin Maynard, Business Development Director at Imprint Pharmaceuticals Ltd, investigates the solublisation and recovery of injectable pharmaceutical materials, and the importance of usability and safety for end users

Many injectable drugs need to be reconstituted either at home or in the clinic. Special devices have been developed to improve the reproducibility, simplicity and safety of the reconstitution of these therapies for end users, including healthcare workers and patients.

Pharmaceutical companies are becoming ever more successful in bringing the fruits of the human genome project to market. Treatment of diseases such as cancer, rheumatoid arthritis, Crohn’s disease and diabetes are being transformed by these therapies. However, many of the therapies require injection and, hence, come with all the complications, both technical and presentational, that injectable therapies bring.

Many of these therapies require frequent injections; depending on the nature of the disease and the patient’s individual condition, those injections could be weekly, daily, or even more frequent.

Many injectable therapeutics are stored as powders; they are more stable in this form. Therapeutics stored as a powder need to be solublised with a liquid diluent and transferred to an injection device before being injected, resulting in an additional operation for untrained users to carry out. This step can be quite complex, with multiple variants in the reconstitution process depending on the therapy, the delivery device and the user’s setting and knowledge. This creates significant issues for those unaware of the problem.


Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer
Kevin Maynard is the Business Development Director of Imprint Pharmaceuticals Ltd, a company focused on providing solutions to the reconstitution and delivery of complex formulations. Over the last 10 years, Kevin has concentrated his efforts on providing clients with practical technology to solve some of the most intractable problems in managing complex fluids at the bedside or clinic. He has a PhD in Pharmacology and 20 years’ experience in drug delivery, cancer biology and therapeutic formulations.
spacer
Kevin Maynard
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

SEKISUI XenoTech Receives New US Patent for a Method to Evaluate Xenobiotics as Immune-Modulators of Drug Transport and Metabolism in Hepatocytes

Kansas City, KS- SEKISUI XenoTech has been awarded US patent # 10,648,968 “In vitro test system to evaluate xenobiotics as immune-modulators of drug transport and metabolism in human hepatocytes.”
More info >>

White Papers

Cleaning Validation: What do you need to consider to ensure a successful outcome?

RSSL

Cross contamination must be avoided in the Pharmaceutical industry at all costs and successful cleaning validation ensures that patients are not put at risk due to cross contamination. The process can be divided into a number of sections each of which must be fully understood and areas of concern addressed to ensure a successful outcome across the entire process. This spans both the manufacturing and subsequent analytical and microbological support. The data used to confirm a positive/successful cleaning validation is underpinned by the results of validated analytical methods. It is essential that these results are truly representative as patient safety is based upon the absence of equipment residues. So what are those areas of concern, what affects your ability to get a successful outcome and what do you need to consider when carrying out a Cleaning Validation exercise?
More info >>

 
Industry Events

World Vaccine Congress Europe

18-21 October 2020, Barcelona, Spain

The World Vaccine Congress is an award-winning series of conferences and exhibitions that have grown to become the largest and most established vaccine meeting of its kind across the globe. Our credibility is show through the prestigious scientific advisory board that spend months of hard work creating a new and topical agenda, year on year.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement