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Pharmaceutical Manufacturing and Packing Sourcer

pmps
Spring 2008
At the cutting edge of the latest industry developments, Samedan is adept at keeping the information you need at your fingertips. PMPS provides a unique platform of communication for the market across Europe, North America and the rest of the developed world. To find out what's hot in the world of pharmaceuticals, take a look below at the range of articles featured in this issue of PMPS.
   
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Manufacturing
There are major benefits on offer to those that implement a strategy to help manage data and knowledge throughout the drug development cycle; Pietro Forgione at IDBS explores the options.  
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Dave Scott of Tepnel Research Products & Services considers why the number of drugs receiving approval has shrunk, claiming it is largely due to failures in stability testing.  
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As pharmaceutical packaging companies are on the lookout for innovative technologies, Bengt Stom of ABB Robotics examines those aiming to to reduce costs, offer greater pack varieties and add value through packaging design.  
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Steve Hemsley from Lanner explores ways that companies can ensure that they are achieving optimal levels of efficiency in order to stay ahead of the pack.  
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Drug Delivery 
Prefilled syringes are showing themselves to be increasingly appealing due to the wide range of benefits they offer to both pharmaceutical companies and patients. Manfred Zurkirch at Dividella AG investigates how recent developments will affect the future of this technology.  
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Automatic injection devices are becoming an ever-more practical drug delivery system, and as such the demand for them is always growing. Tim Barrow-Williams and Rosie Burnell at PA Consulting consider the benefits the technology affords to both businesses and end-users.  
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Drug administration methods are a crucial consideration in the success of a product. Patrice Lewko at Rexam measures how transdermal gels are becoming a more realistic option for pharmaceutical manufacturers, weighing this against the challenges that lie ahead in finding suitable dosing devices.  
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Nasal and pulmonary delivery methods have been successful in safely administering drugs to patients. However, they make it difficult for the patient to keep track of their dosage. Pierre Carlotti at Valois proposes how drug delivery devices can evolve to help counter this problem.  
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Formulations, Ingredients and Excipients
The outsourcing of inhalation device development is commonplace today – Jan Andersson at Bang & Olufsen Medicom analyses why the development of pMDIs is being handed over to specialised suppliers, and what advantages this can bring.  
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Until now, omega 3 has been better known as a generic nutritional supplement; Dr Miquel Mir of Croda Europe Ltd insists that we should change our perception of this fatty acid as it can have a very positive effect in helping to reduce inflammation.  
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As the importation of pharmaceutical products into Europe is becoming more strictly controlled, Ken Caldicott at Brecon Pharmaceuticals examines the key considerations available to those companies aiming to successfully negotiate this regulatory minefield.  
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In an era of increasingly complex drug formulations, it is important to develop technologies capable of analysing such products. Detlef Beckers at PANalytical BV proposes X-ray powder diffraction as an ideal solution.  
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IT and Logistics
Rodney Steel of the BCMPA advises how finding the right specialist to handle the manufacturing, packing and delivering of goods could prove a worthwhile investment.  
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Andy Silver of BSS Industrial outlines why it is important to check that the company supplying the component parts of your production line understands each challenge.  
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PACKING, PACKAGING & ANTI-COUNTERFEITING
Thomas Völcker of Schreiner ProSecure discusses the reasons why the pharmaceutical arena is so appealing to counterfeiters – an increasingly concerning problem for every aspect of the industry. He analyses how badly the industry is affected by this problem; and the latest security measures attempting to tackle the issue.  
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The problem of patients being supplied with counterfeit drugs increases; David Lyon at GS1 UK analyses new security measures being adopted by pharmaceutical companies.  
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Dr Thomas Dries at Honeywell Specialty Films, along with Charles Rowlands and Amy Morgan at RM Consulting, investigates how thermoformed primary packaging can offer companies a new lease of life.  
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Storing and packaging a drug in a safe manner is a vital consideration in its development cycle. Adrian Possumato of Multisorb Technologies discusses pseudo-empirical modelling as regards this issue.  
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Bill Martineau of the Freedonia Group explains how to improve the safety, effectiveness and ease of IV administration and injectable drug delivery.  
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COOL CHAIN
Recent developments in French guidelines on pharmaceutical logistics are having a significant effect on packaging specification and procedures both from and within France. Tim Jennings of Emball’iso takes a closer look at the changes afoot.  
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Robert Simpson of Jet Environmental investigates the methods available to help remedy the problem of managing extreme changes in temperature.  
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PATIENT COMPLIANCE
As pressure increases on the pharmaceutical industry to offer more value for money, David Spackman of MeadWestVaco explores the potential impact of investment in packaging in order to improve patient compliance to drug treatments and therefore reduce wastage.  
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A key concern for the pharmaceutical industry is the adherence of patients to their medication regimens – failure to do so results in substantial numbers of prescribed drugs being discarded each year. Tassilo Korab at HCPC examines the methods available to manufacturers to help improve patient adherence rates, and therefore successful treatment.  
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Edited by
Randice Altschul
Chief Executive Officer at Pop Test and Palisades Therapeutics

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