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Pharmaceutical Manufacturing and Packing Sourcer

Polyethylene Glycol Purity

One of the main challenges in the pharmaceutical industry is the ability to produce stable drug formulations. This is especially demanding as many active pharmaceutical ingredients (APIs) respond unstably to oxidation, moisture or pH. Generally, excipients are the major component of any given drug formulation. In the past, pharmaceutical excipients have been viewed as ‘inert’ ingredients that played an insignificant role in the stability of formulations containing APIs. This view is now changing as pharmaceutical formulators have gained a greater awareness of the importance of excipient purity. Excipient impurities can accelerate the degradation of the API as well as destabilising emulsions, causing skin and cellular irritation (1,2) and promoting gelatin cross-linking (3) in both soft gelatin and hard gelatin capsules.

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Nigel Langley, PhD, is currently Technical Director – Health Care for Croda Inc, Edison, New Jersey. He obtained a BSC Hons and PhD from the University of Hull, UK and then undertook a two-year Postdoctoral project (natural product synthesis) at Leeds University, UK. He joined Croda in 1984 and has held various technical positions in four Croda Companies. He spent three years as Technical Director of Croda Japan before joining Croda Inc (USA) in 2001. Nigel’s research interests are in lipid chemistry both for Pharmaceutical and Personal Care applications.

Karen H Chen is currently Marketing Manager of Health Care at Croda Inc (USA). She holds a Bachelors degree in Biology and Chemistry from Rutgers University and a Masters degree in Cosmetic Science from Fairleigh Dickinson University. She began her career in the cosmetic industry as a personal care formulator at Johnson & Johnson and a skin care formulator at Avon Products. She later moved into technical sales for Biosil Technologies and Wacker Chemical Corporation prior to her start at Croda Inc (USA) as the Marketing Manager of Skin Care and Makeup. Karen is active in the New York Chapter of the Society of Cosmetic Chemists (NYSCC) having held the positions of Treasurer and Photographer, a position she currently occupies. In addition she also serves on the NYSCC Supplier’s Day Committee and the NYSCC Scholarship Committee.

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Nigel Langley
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Karen H Chen
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