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European Biopharmaceutical Review

ebr
Autumn 2019

   
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In Brief
In Brief

Vax Populi

EBR’s Industry Advisor, Emile Bellott, discusses the health achievement of vaccinations against infectious diseases in the post-industrial era, and how immunisation is essential to continue saving millions of lives every year.

 
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Features
Anti-Idiotypic Antibodies

Robust Method Development for Biologics and Biosimilars

Amanda Turner at Bio-Rad Laboratories examines the factors that enable the demand for biological medicines to evolve and expand, such as the introduction of lower-cost biosimilars, or the ongoing identification of new drug targets.

 
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Preclinical Oncological Research

PET Technology and Tumour Progression

Dr Todd Sasser at Bruker BioSpin writes on how, with the advancements of PET scanning, oncologists are now better able to understand the development of cancers and tumours by better highlighting their morphology and other biomarkers.

 
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Accelerating Process Development

Simply Good Monitoring

Paul Kroll and Alexandra Hofer at Securecell AG articulate how digitisation can accelerate process development in relation to the analysis of liquid samples.
 
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High-Productivity Membrane Chromatography

The Next-Generation Purification of Monoclonal Antibodies

Gary Skarja at Merck examines the key developments in mAb manufacturing, including the benefits that address productivity and cost challenges in a singleuse format.

 
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Challenges in Cellular, Tissue, and Gene Therapy Products

Drug Development Decisions

Cost control in drug development is always at the forefront of manufacturer’s minds, and Zeb Younes and Zaklina Buljovcic at PharmaLex examine how automation and decentralising the manufacturing process can help achieve this goal in the long run.
 
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Developments in Artificial Intelligence

Focusing on Target Safety

Although in its infancy, Ruth Roberts at ApconiX describes how artificial intelligence can help reduce the cost and the amount of product failures in regard to drug development and creation.
 
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Standardising Conditions for Extractables Testing

Exhaustive Extraction

Simone Carrara and Michele Vasso at Eurofins illustrate the importance of extractables and leachables to ensure drug efficacy, and that the product remains in optimal condition to interact with the patient.
 
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bullet Stem Cell Research
Stem Cell Therapy

Recombinant Human Albumin

Cryopreservation and stem cell therapies are facing major changes and advancements, Dr Phil Morton and Dr Daniel Shelly at Albumedix discuss how albumin is useful across the cell therapy value chain.


 
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Live Cell Transport

The Rising Star

The way in which we transport existing cell shipments is continuously being optimised, and Dr Corné Swart at Cellbox Solutions looks into these new devices that allow cells to survive compared to traditional methods.
 
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rare diseases
Orphan Drugs and Rare Diseases

Patient Voices in the Industry

When considering the development of orphan drugs, the patients that suffer from the diseases and help process drug development in clinical trials also have to be considered, write William C Maier and Kelly Franchetti at ICON.
 
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dna and rna sequencing
Biopharmaceutical Applications

The Advantages of Long-Read Sequencing

Jonas Korlach at Pacific Biosciences discusses the improvements in long-read sequencing technology, and the applications it may have in the discovery of new drugs.
 
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Advances in Oncology

Advancing Liquid Biopsies

Mark Li at Resolution Bioscience examines why liquid biopsies are now becoming more commonly used compared to tissue biopsies.
 
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cannabis-based drugs
The Potential of Medical Cannabis

Budding Opportunities for Pharma

Shifting attitudes towards cannabis-based medicines are making them more appealing to drug developers, which will in turn help patients who need these drugs, writes Callum McGuinn at Mewburn Ellis.
 
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The Future of Clinical Research on Medical Cannabis

Trial by Fire

Dr Mark A Ware at Canopy Growth Corporation describes the changes in drug policy in recent times surrounding cannabis-based drugs, and the advantages they may have in treating patients.
 
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Published quarterly in
January, April,
July, and October

News and Press Releases

Sphere Fluidics Closes a $4.8 million USD (£3.7 million) Funding Round

Cambridge, UK, 10 June 2019: Sphere Fluidics, a company commercializing single cell analysis systems underpinned by its patented picodroplet technology, announced today that it has closed an additional tranche of investment of $2.9 million (£2.2 million), securing a total of $4.8 million (£3.7 million) in investment. The funding will be used as working capital for the Company’s Cyto-Mine® Single Cell Analysis System, expansion of the UK facility and enable the doubling of personnel through the opening of a new US Sales Office and Demo Lab in California.
More info >>

White Papers

Inhaler Adherence: Exploring Key Factors

Aptar Pharma

Aptar Pharma recently hosted an expert panel roundtable on “Inhaler Adherence”. This international scientific forum was held in Paris, France on November 29th 2013. The roundtable was organized to explore and exchange views on the issues which may influence inhaler adherence/ compliance with a particular focus on asthma and C.O.P.D. therapies and their corresponding inhaler devices (MDIs, DPIs).
More info >>

Industry Events

CPhI & P-MEC India

26-28 November 2019, India Expo Centre, Greater Noida, Delhi NCR, India

As the pharma industry looks increasingly towards India forhigh quality, low   cost pharma solutions, CPhI & P-MEC Indiais the ideal event for companies wanting to pick up on the latest trends and innovations the market has to offer. At CPhI & P-MEC India, you will meet the movers and shakers from India’s pharma machinery, technology and ingredients industries, giving you a competitive advantage that will help grow your business.
More info >>

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