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European Biopharmaceutical Review

ebr
Spring 2016

   
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Editor’s Letter

EBR’s Editor Deborah O’Neil ponders the impact of the digital age on pharma and the improved data handling this facilitates, along with other focus features in this edition.
 
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Science and Innovation
Wearable Technology

Technically Speaking


Despite the growing popularity of health technologies, much uncertainty still surrounds digital healthcare and the exact definition of this ever-expanding field, say CMS Life Sciences Group’s Sarah Hanson and Laura Lucy.
 
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Smart Healthcare

Intelligent Design


The Internet of Things is the latest wave of technology sweeping the healthcare landscape, observes Jonathan Wilkins at European Automation – who assesses some of the radical and potentially life-saving technologies it could bring.
 
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Automation Advances

Rise of the Machines


Recent advances in cognitive computing could drastically shake up the industry, states IBM's Institute for Business Value’s Heather Fraser, enabling fast and more accurate decisionmaking by healthcare professionals to enhance patient care.
 
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Discovery Technology
Biologics Characterisation

Compare the Market


The characterisation of biological products has become ever-more reliant on advanced technology, states Fredrik Sundberg at GE Healthcare. He explains why surface plasmon resonance and sensorgram comparison offer vast benefits.
 
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Molecular Analysis

Measuring Up Nicely


A “fast, absolute and inherently simple method”, the emerging Taylor dispersion analysis system offers unique benefits compared to other long-established techniques, say Dr Steve Carrington and Dr Lisa Newey-Keane at Malvern Instruments.
 
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Microscopy Advances

Culture Shift


The modern cell culture microscope is continuing to assist researchers improve workflow efficiency and make new discoveries. Olympus Europa’s Joachim Kirschner highlights where he believes light microscopy can take science in the near future.
 
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Biodevelopment and Manufacturing
Supply Chain Agility

Quick on the Draw


Agility – within all stages of pharma manufacturing – is key to achieving success in company goals, believes Mark Evenepoel at AMPLEXOR Life Sciences.
 
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Sample Preservation

From Collection to Destruction


All biological samples, whether successful or not, could prove valuable in future biomarker studies – which is why extreme care must be taken when handling and transporting these highly delicate products, explains Eric Hayashi at LabConnect.
 
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CANCER FOCUS
Q&A: Rare Cancer Treatments

Making Waves


As recent reports reveal that acute myeloid leukaemia – a rare cancer form – is expected to rise with an ageing population, Actinium Pharmaceuticals Dragan Cicic describes how a promising new radio-immunotherapy treatment could boost patient survival rates.
 
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Immunotherapy Advances

Armed Against Cancer


CAR-T cell therapy – which involves engineering patients’ own immune cells to detect and attack tumours – is giving rise to a new generation of groundbreaking cancer treatments, including NKG2D, which could wipe out up to 80% of cancers, reports Christian Homsy at Celyad.
 
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Oncology Research

Modify This


Alfred Hansel and Martina Schmitz at oncgnostics GmbH explain the growing popularity of epigenetic modifications in cancer treatment.
 
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BUSINESS STRATEGY
Medical Affairs

Surveying Change


Dr Fabio Gambini, Paolo Morelli and Mary Wieder at PM Clinical talks about the relatively new Medical Sciences Liaison role, and how plans to outsource this vital function could impact on the industry.
 
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In Brief

Eye of the Storm


Emile Bellott comments on the growing prominence of biosimilars, which are currently gaining visibility at the highest government levels, and some of the challenges this presents.
 
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RESEARCH AND DEVELOPMENT
Protein Structure

Multiple Choices


Before any biologic drug can be approved, the first crucial step is to obtain a full and accurate profile of the protein molecule – which can only be achieved by using a combination of techniques, states Ińigo Rodriguez-Mendieta at SGS.
 
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Edited by
Dr Deborah O'Neil,
Chief Executive and Scientific Officer,
NovaBiotics Ltd
Published quarterly in
January, April,
July and October

News and Press Releases

For New Product Development Meet Reliance at Analytica

Reliance Precision “Reliance”, a specialist engineering company, will be in Hall B2, Booth 123 at Analytica to discuss its 1, 2, 3 design and development approach of 1, modelling, 2, reliability and 3, validation which makes Reliance the partner of choice for life science and diagnostic equipment manufacturers looking for quality components and sub-assemblies right through to full product design.
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White Papers

PROTEIN:PROTEIN INTERACTION ANALYSIS

IBA GmbH

Groth et al., 2007 and Jasencakova et al., 2010 Protein:protein-interactions (PPI) govern almost all important processes in living organisms. Thus, their rapid and accurate determination and investigation is a major challenge in life sciences. The extremely efficient and fast One-STrEP (Twin-Strep) system is suitable for the isolation of functional protein complexes and subsequent mass spectrometry analysis leads to the identification of protein complex components (Junttila et al., 2005) as it is shown in the following studies.
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Industry Events

Clinical Operations in Oncology East Coast 2016

13-14 July 2016, Boston, MA

Clinical Operations in Oncology Trials East Coast returns to Boston for 13-14 July 2016, to build on the success of the 2015 event.
More info >>

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