home > news > detailed info

Specialized expertise that gives you an inside edge

Vetter Pharma International GmbH

Tap into the knowledge of specialists with decades of experience identifying and solving difficult challenges. From technical obstacles such as siliconization and lyophilization to strategic issues such as life cycle planning, Vetter’s integrated team approach brings together the right experts for your compound’s precise requirements.

This kind of expertise is at the heart of what makes a CDMO a valuable partner for your injectable. When you consider all the criteria your outsourcing partner should meet – experience with a broad range of injectables, deep scientific and manufacturing resources, financial stability, and even a commonly shared vision – a partner whose expertise goes above and beyond clearly stands out.

Production Excellence (ProdEx)
Combining optimized processes with high quality

In the production of high-quality pharmaceuticals, aiming for excellence in all production areas is the overarching goal of a well-defined and holistic course of action for process optimization. The strategy is to further simplify and streamline processes, improving their efficiency and effectiveness while reducing human errors. Although challenging, this offers significant potential to fulfill the increasing expectations of customers and regulatory bodies for ever more efficient and flexible production processes.

Essential to this task is a pathway that involves an intelligently designed internal optimization process that takes a holistic approach by spanning the entire production system. This includes processes, employees and technologies across all production locations, departments and hierarchies of the production. The result is a realignment and development of the entire system in the best way possible.

ProdEx is an effective method for ongoing process optimization

The internal optimization process of production, called ProdEx (Production Excellence), is indispensable at Vetter for a positive development of a production that is highly regulated, customer-transparent, complex and know-how intensive. With ProdEx, achieving sustainable results is accomplished by creating a team of internal experts and the involvement of all executives. The goal is to design and implement solutions ‘from production for production’ using internal resources. The team manages the launch and implementation of the measures and controls the overall coordination of subsequent steps designed to further improve processes. The result is a holistic approach for all production locations as well as with other technical departments.

Achieving the best possible results from the implementation of these measures is accomplished by combining and customizing aspects of a large spectrum of known and self-developed process optimization methods. These include:

  • Lean Management
  • Six Sigma
  • Statistics
  • Kanban
  • Gemba-Walks ‘Keep-It-Simple-Approach’

ProdEx generates successful results

Vetter has been applying ProdEx to its manufacturing process for the past four years. Process optimizations resulting from ProdEx demonstrate significant results. These include:

1. Systematic waste disposal– checking and terminating processes that have no identifiable value-added elements:
>> Total work reduction for affected employees ranging from 10 minutes to 2 hours per day/per employee
>> Reduction of the burden for employees in production and surrounding areas

2. Implementation of a digital micro-malfunction management system
>> Increase of technical availability in aseptic filling, packaging and automated visual inspection – increase in performance up to 12%

3. Development of a comprehensive program to avoid human error based on the pillars ‘Process – Organization – Human Factors’
>> Significant reduction of the human error rate by 15% within three years

These examples illustrate that it is possible to simultaneously combine widening process optimization and increasing quality.

ProdEx results – A critical contribution to the results of a company-wide optimization system

Through ProdEx, Vetter has improved production flexibility and increased efficiency, all while meeting an increase in quality assurance requirements from customers and regulatory authorities. At Vetter, aiming for excellence in all production areas is the overarching goal of ProdEx. The results achieved are integral to the Vetter Optimization System (VOS), which paves the way for a company-wide continuous improvement process.

“Those who don’t believe they can get better have stopped being good. "

- Philip Rosenthal
phone +49 751 3700 0
email Eywiesenstraße 5, 88212 Ravensburg, Germany
Print this page
Send to a friend
News and Press Releases

Protagen Protein Services (PPS) expands capabilities for aggregate analytics to include dynamic light scattering (DLS)

Protein aggregation is a common challenge in the manufacturing of biological products. As one of the most sensitive techniques for the detection of aggregates, dynamic light scattering (DLS) provides a simple, fast and non-destructive testing method. An innovative technique based on a unique cuvette layout allows for accurate measurements with as little as a single µL of solution.
More info >>

White Papers

Delivering Fit For Purpose Biomanufacturing CHO Cell Lines

Fujifilm Diosynth Biotechnologies

The challenge during mammalian cell line development is to identify and isolate stable, high expressing cell lines producing product with the appropriate critical product quality attributes rapidly, reproducibly and with relative ease. Obtaining a host cell line that inherently exhibits desirable biomanufacturing attributes can therefore have a significantly positive effect on the identification of recombinant cell lines with desired traits during cell line development screens. In this study, we demonstrate that it is possible to exploit intrinsic heterogeneity within host cell populations and identify host cell lines which are more “fit for purpose”.
More info >>

Industry Events

12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology

8-11 February 2021, Vienna, Austria

In continuation of the very successful scientific meetings in Budapest, Paris, Berlin, Florence, Geneva, Barcelona, Malta, Istanbul, Lisbon, Glasgow and Granada, the 12th PBP World will be held in Vienna from 8-11 Feb 2021. This every two year held conference has gained an ever increasing impact among the pharmaceutical scientists: With up to 1000 submitted abstracts and about 1300 participants it has become a well-established major meeting, attracting scientists from all over the world.
More info >>

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement