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GE Healthcare Life Sciences

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email P.O. Box 643065 Pittsburgh, PA 15264-3065 United States of America

The Flexible Factory Concept: A flexible bioprocessing platform to meet the changing needs of biomanufacturing

For the past several years, the biopharma industry has been buffeted by dynamic market conditions that are rapidly reshaping manufacturing requirements. These factors include:

• The rise of small-market pharmaceuticals that do not require the production scale of the previous “blockbuster” drug model

• Increased titers and process productivity that generate more bulk-product within a much smaller manufacturing footprint

• The emergence of biosimilars and continued evolution of healthcare reform, which will increasingly pressure drug pricing and require greater cost discipline

• Greater competition and shorter patent protection timelines, which will further ratchet up time-to-market pressures

• Tighter capital markets that will create heightened scrutiny for all new investment projects
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