spacer
home > white papers > Modifying MDI Canister Surfaces to Improve Drug Stability & Drug Delivery - Presspart Manufacturing Ltd
WHITE PAPERS
logo_Presspart_5.jpg

Presspart Manufacturing Ltd

phone +44 1254 584131
email chad.mayoh@presspart.com
web http://www.presspart.com
email Whitebirk Industrial Estate, Blackburn, BB1 5RF

Modifying MDI Canister Surfaces to Improve Drug Stability & Drug Delivery

Hydrofluoroalkane (HFA)-based propellants are widely used in modern metered-dose inhalers (MDIs), due to their lack hazardous and environmentally-damaging effects. However, an HFA's active pharmaceutical ingredient can interact with the canister substrate, causing deposition of the drug to the canister walls, or interact with the solution, causing degradation and resulting in increased impurity levels. Over the past few years, a number of surface coatings have been developed that can be applied to MDI canisters and valve components, to protect the contents from deposition and degradation. More recently, plasma processes have been developed to modify and improve the surface energy performance of a MDI canister. This approach has a number of advantages to alternative coatings but requires careful optimisation to ensure the highest quality finish and MDI performance. Richard Turner, Business Development Director, Presspart Manufacturing Ltd, explains.
Modifying MDI Canister Surfaces to Improve Drug Stability & Drug Delivery
spacer

Member login

E-mail address:

Password:
Remember me


News and Press Releases

Enjoy form function and comfort with Teknomek’s new class 5 certified PU chair

Teknomek has released a strong, durable and soft PU (poly-urethane) chair designed for use in production, laboratory and healthcare environments. The product is clean room grade 5 certified and can accommodate weights of up to 150 kg.
More info >>


White Papers

Successfully managing the unique demands of cell therapy supply chains

PCI Pharma Services

Cell therapy professionals joined a specialist webinar by industry experts from PCI Clinical Services and TrakCel, addressing the unique complexity of an autologous therapy supply chain. Hosted by European Pharmaceutical Manufacturer magazine, the webinar was delivered by Rachel Griffiths, Associate Director, Technical Services, PCI Clinincal Services, and Dr. Matthew Lakelin, Vice President, Scientific Affairs and Business Development, TrakCel . Here, we present the white paper from that webinar event.
More info >>


Industry Events

SMI Immuno-Oncology Conference

25-27 September 2018, Copthorne Tara Hotel, London, UK

Immuno-Oncology is a fast-paced field with massive potential to deliver successful and durable cancer therapies, and SMi's Immuno-Oncology Conference will focus on a few key areas of the field with a representation of the whole industry under each area. These areas will be drawn together to look towards the future of Immuno-oncology and how the field can progress.
More info >>


©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement