BACHEM
***BACHEM. PIONEERING PARTNER FOR PEPTIDES***
Bachem is the leading independent supplier of peptidic active pharmaceutical
ingredients (APIs) for the human and veterinary pharmaceutical market. Since its
foundation in 1971, Bachem’s concepts and technologies pioneered the industrial
peptide manufacturing. Our pioneering mindset drives us to continue developing
innovations and offering all integrated services needed to bring our partners
breakthroughs to market.
***RESEACH:
Bachem offers the world¡¦s largest collection of amino acid derivatives, linkers
and reagents for peptide synthesis. In addition, solid phase supports for
different synthesis strategies are available. Other key research products are
bioactive peptides, enzyme substrates and inhibitors as well as organic
molecules. New products are continuously added to meet new demands for
innovative and high quality research chemicals.
***PRECLINICAL DEVELOPMENT:
Our custom-made peptide service supports lead finding and optimization during
preclinical development. Close collaboration with Bachem experts allows
further refining of target compounds and consequent project advancement.
A strong partnership is key to come up with pioneering concepts and molecules
to bring into clinical development.
***CLINICAL DEVELOPMENT:
Our partners can trust in our support and guidance from early development and
selection of the lead compound, throughout all clinical phases and final drug
approval. Each production step is scrutinized in order to guarantee
manufacturing reproducibility and scale-up possibilities. Process validation
and control is the result of the intense partnership between Bachem and our
customers.
***PEPTIDE DRUGS:
As a leading peptide Contract Manufacturing Organization, we guarantee the
reliable supply of the drug substance by coordinating our activities closely
with our partners. Bachem is currently involved in more than 150 cGMP
development projects targeting new chemical entities (NCEs) and offers a
range of more than 30 generic drug substances. We have the capacity to
produce peptide APIs from gram scale up to annual quantities of hundreds of
kilograms and small molecules APIs from gram scale up to annual quantities of
tens of tons. The FDA and local authorities regularly inspect our GMP
manufacturing facilities, located in Switzerland and the United States.
In addition to close to 50 years of experience in the manufacture of drug
substance, Bachem also has a strong regulatory background. We are well
prepared to fully support our customers with the required regulatory
documentation such as drug master files (DMFs). For complex development
projects, we support our customers with dedicated project teams comprising
of our experts from R&D, production, quality control, quality assurance and
regulatory affairs. A team of experienced Business Development Managers and
Generics Managers look forward to working with our customers for their future
requirements.
Headquartered in Switzerland with subsidiaries in Europe, the US and Asia,
the Bachem group has a global reach. Bachem shows total commitment to quality,
innovation and partnership.
