Natoli Engineering Company, Inc.

Natoli Engineering Company, Inc., is the recognized global leader in tablet press tooling manufacturing. Founded on the uncompromising principle to manufacture and deliver only the highest quality tablet compression tooling, presses and replacement parts at a fair price with exceptional customer service, Natoli has been at the forefront of the tablet compression industry for more than 40 years. Our state-of-the-art manufacturing facilities, award-winning engineering team and dedicated production crew enables us to offer clients competitive pricing without compromising personalized customer service.

Technical Services

  • Tooling Design
  • Tablet Design
  • Tablet Press Refurbishing
  • Technical Training
  • Formulation Testing and Analysis
  • Metallurgical Analysis

Facilities

Located in St. Charles, Missouri, Natoli’s 10-acre campus includes administrative, manufacturing, refurbishing, training, and laboratory and scientific research facilities.

Major Products/Services

Tablet Compression Tooling: Natoli manufactures single and multi-tip punches and dies of unparalleled quality – available in simple and complex designs from more than 15 steel types and 10 specialty coatings.

Tablet presses: A full range of cost-effective options from single-station R&D laboratory models to heavy-duty rotary presses with extra fill capabilities and extended dwell times.

Tablet Press Replacement Parts: Natoli maintains an extensive inventory of tablet press replacement parts and turrets for virtually all press types with most parts available for same day shipping.

Tablet Compression Accessories Catalog: We offer the most comprehensive accessories catalog in the industry featuring hundreds of items to help you care for, analyze and prolong the life of your tooling and equipment.

Technical Training: Learn the latest tablet technologies while improving processes through hands-on training from world-renowned academic and industry experts.

Tablet and Tooling Design: Natoli Engineering provide expert tablet and tool design services to ensure tablet quality, maximize production and enhance product lifecycle. We also offer a free web-based tablet design software, TabletCAD which enables tablet manufacturers to design their own tablets to desired specifications.

 


Markets Served

We serve the pharmaceutical, veterinary, nutritional, confectionery and industrial tableting industries through distributors in major markets around the world, including South America, Europe, the Middle East, Africa, and the Asia-Pacific region.

Natoli Engineering Company, Inc.

28 Research Park Circle

Saint Charles, MO 63304

+1 636 926 8900

info@natoli.com 

Natoli Engineering Introduces EZ Level Feeder Base Leveling System

9 May 2025 -- Missouri, US -- Natoli Engineering, the global leader in tablet compression tooling, is unveiling the EZ Level™ Feeder Base Leveling System, Part Number SU 2970. This innovative design eliminates long setup times, enhances accuracy and minimizes formulation loss, and increases production time. You will no longer need to settle for “close...

New Natoli Tablet Press & Tooling Training Scheduled

ST. CHARLES, MO (May 9, 2022) ó For years, one of Natoli Engineeringís competitive advantage has been our broad array of training courses. Where many companies only sell tablet press tooling and machinery, Natoli offers in-house training seminars that give our customers an opportunity to learn how to operate and maintain the equipment to peak...

Natoli Engineering Company Introduces Colored Tooling Storage Boxes

ST. CHARLES, MO., U.S. (Aug 7, 2017) ó Natoli Engineering Company, Inc. continues to satisfy customer needs by announcing an exclusive addition to their Tablet Compression Accessories Catalog, red and black colored tooling storage boxes. Like their standard cream storage boxes, the new colored boxes are constructed of easy-to-clean, FDA compliant materials. The new color...

Natoli Engineering Company Now Offers Plastic Media for Automated Polishing

ST. CHARLES, MO., U.S. (July 26, 2017) ó Natoli Engineering Company, Inc. announces an addition to their Tablet Compression Accessories CatalogóPolyPlus and PolyPlus Prime plastic media for use with automated polishing systems. Natoli strives to offer solutions to customer problems in every area of the tablet compression process. If you are using drag finishing (automated...

Natoli Engineering Company Announces Metal Detectable Dust Cups and Bellows

ST. CHARLES, MO., U.S. (June 12, 2017) ó Natoli Engineering Company, Inc announces an addition to their Tablet Compression Accessories Catalog ó metal detectable dust cups and bellows. About Dust Cups and Bellows Dust cups are a low-cost solution that aid in keeping lubrication off die tables and out of tablets. Bellows provide additional protection...

Tablet Compression Resource Launches New Training Opportunities

Tablet Compression Resource, a division of Natoli Engineering Company, Inc., has announced the launch of new training courses in 2017 at their Long Island facility.

Natoli Engineering Company Opens Facility in Poland

ST. CHARLES, MO., U.S. (March 16, 2017) - Natoli is expanding their European presence by launching its newest business division, Natoli International, and with that, the opening of the Natoli Poland service & distribution facility, located in Poland. This 4,000-square foot structure will feature live equipment demonstrations, technical training, tablet press replacement parts distribution and...

Natoli Announces 2017 Technical Training Course Schedule

ST. CHARLES, MO., U.S. (Oct. 13, 2016) ó Space is limited is a phrase youíll be hearing a lot more of in the coming months as Natoli Engineering rolls out its 2017 technical training course schedule, headlining: Basics of Tablet Manufacturing and Troubleshooting. The dates for 2017 are: January 24-26 April 25-27 August 22-24 November...
28 Research Park Circle, Saint Charles, MO 63304, US

+1 636 926 8900