Sartorius Supports the Development of the First Vaccine Candidate Against the Novel Coronavirus to Enter Clinical Trials
March 25, 2017 – Pharmaceutical –
SHANGHAI, China, March 25, 2020 / B3C newswire / — Sartorius,
a leading international partner of life science research and the
biopharmaceutical industry, has supported CanSino Biologics Inc.
(‘CanSinoBIO’) and Maj. Gen. Chen Weiís team at the Institute of
Bioengineering at the Academy of Military Medical Sciences (‘Institute
of Bioengineering’) in China in their development of the first vaccine
candidate against the novel coronavirus SARS-CoV-2 to enter clinical
trials. CanSinoBIO and the Institute of Bioengineering used Sartoriusí
BIOSTAT STR single-use bioreactor system for the upstream preparation
of the recombinant vaccine, thus ensuring the rapid linear amplification
of the adenovirus vector (Ad5-nCoV) and ultimately saving time during
development.
a leading international partner of life science research and the
biopharmaceutical industry, has supported CanSino Biologics Inc.
(‘CanSinoBIO’) and Maj. Gen. Chen Weiís team at the Institute of
Bioengineering at the Academy of Military Medical Sciences (‘Institute
of Bioengineering’) in China in their development of the first vaccine
candidate against the novel coronavirus SARS-CoV-2 to enter clinical
trials. CanSinoBIO and the Institute of Bioengineering used Sartoriusí
BIOSTAT STR single-use bioreactor system for the upstream preparation
of the recombinant vaccine, thus ensuring the rapid linear amplification
of the adenovirus vector (Ad5-nCoV) and ultimately saving time during
development.
The BIOSTAT STR single-use bioreactor system comes with updated BioPAT toolbox for process monitoring, as well as Flexsafe STR integrated, single-use bioprocess bags. It has been proven to be used for vaccine manufacturing because it offers rapid scalability and flexibility to adapt to fluctuating demand. The single use bags prevent cross-contamination, and reduce the time needed for washing and sanitation typical in stainless steel bioreactors. As such, the amount of time needed to prepare a vector for a vaccine is shortened from several months to (several) weeks.
‘We are pleased that we can help our clients and partners accelerate vaccine development while maintaining compliance with safety protocols, thereby allowing us to contribute to better health for more people,’ said Huang Xian, Head of Marketing at Sartorius BPS China. ‘The Sartorius team is making every effort to quickly allocate the staff and equipment needed to support the early stages of vaccine development during this high-risk period. We hope that Ad5-nCoV will achieve approval as early as possible, so it can help stop the spread of the novel coronavirus worldwide.’
This is the second collaboration from Sartorius, CanSinoBIO, and the Institute of Bioengineering to accelerate vaccine development. In October 2017, Sartoriusí BIOSTAT STR50 bioreactor system was used during CanSinoBIOís and the Institute of Bioengineeringís joint development of a recombinant vaccine against Ebola virus disease. This was the first registered Ebola vaccine in the world.
About Sartorius
The Sartorius Group is a leading international partner of life science research and the biopharmaceutical industry. With innovative laboratory instruments and consumables, the Groupís Lab Products & Services Division concentrates on serving the needs of laboratories performing research and quality control at pharma and biopharma companies and those of academic research institutes. The Bioprocess Solutions Division with its broad product portfolio focusing on single-use solutions helps customers to manufacture biotech medications and vaccines safely and efficiently. The Group has been annually growing by double digits on average and has been regularly expanding its portfolio by acquisitions of complementary technologies. In fiscal 2019, the company earned sales revenue of some 1.83 billion euros according to preliminary figures. At the end of 2019, more than 9,000 people work at the Groupís approximately 60 manufacturing and sales sites, serving customers around the globe.
Contact
Timo Lindemann
Corporate Communications
+49 (0)551.308.4724
sartorius.com
Keywords: Bioreactors; Pharmaceutical Production; Manufacturing; Biological Products; Automation; SARS Virus; Coronavirus; COVID-19; severe acute respiratory syndrome coronavirus 2; Coronavirus Infections; Vaccines, Synthetic; Bioengineering
Sartorius Corporation, Otto-Brenner-Straße 20, 37079 Goettingen, Germany
