News and Press Releases

New Kite Clinical Research and Real-World Evidence for Yescarta (Axicabtagene ciloleucel) Demonstrate Benefit From Earlier Lines of Treatment

Analysis shows manufacturing of axicabtagene ciloleucel in second-line treatment of relapsed/refractory large B-cell lymphoma can help reduce time from leukaepheresis to infusion vs third-line plus treatment Data builds on previous...

Category: Biotechnology, Clinical Trials, Drug Discovery
Posted: June 14, 2024

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CRISM Therapeutics Corp to continue pioneering R&D at PHTA following listing on the London Stock Exchange

11 June 2024 -- Birmingham, UK -- CRISM Therapeutics Corporation a UK-based pharmaceutical company focused on improving the clinical performance of cancer treatments for solid tumours, has raised £2.0m to...

Category: Biotechnology, Clinical Trials, Drug Delivery, Pharmaceutical
Posted: June 11, 2024

Kingston Chambers, PO Box 173, Road Town Tortola, British Virgin Islands

Oxford Drug Design and CRUK Scotland Institute awarded MRC grant funding to advance novel cancer therapeutics discovery

Collaboration to use genetically engineered mouse models to validate a new approach to cancer therapy 4 June 2024 - United Kingdom - The CRUK (Cancer Research UK) Scotland Institute and Oxford...

Category: Drug Discovery
Posted: June 10, 2024

Oxford Drug Design Lt,d Oxford Centre for Innovation, New Road, Oxford, OX1 1BY, UK

MediMab Biotherapeutics opens bespoke laboratory facilities, created by Kadans Science Partner, at Abingdon Science Park, UK

New CL2 wet lab purpose-built facilities delivered by Kadans Science Partner will support MediMab Biotherapeutics to identify first-in-class immuno-oncology drugs that can actively target a range of advanced and solid...

Category: Biotechnology, Manufacturing and Packing, Pharmaceutical
Posted: June 6, 2024

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SYS6002 (CRB-701) A Next-Generation Nectin-4 Targeting Antibody Drug Conjugate Continues to Demonstrate Encouraging Safety and Efficacy Observed in Patients with Nectin-4 Positive Tumours in a Clinical Update Presented at ASCO 2024

An additional 19 patients have been enrolled since January 2024 bringing the total to 37 of whom 25 were evaluable for efficacy SYS6002 (CRB-701) demonstrated 44% ORR and 78% DCR in...

Category: Clinical Trials, Drug Discovery, Pharmaceutical
Posted: June 5, 2024

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Kite’s TECARTUS (Brexucabtagene Autoelucel) Demonstrates Sustained Overall Survival in Adult Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia

After more than four years of follow-up in the pivotal ZUMA-3 study, median overall survival was 26 months and four-year overall survival rate was 40% at 48 months Survival benefit...

Category: Biotechnology, Clinical Trials, Pharmaceutical
Posted: June 3, 2024

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Encouraging New Data Presented on Kite’s YESCARTA (Axicabtagene Ciloleucel) for Relapsed/Refractory Central Nervous System Lymphoma  

At median follow-up of 24.2 months, no apparent additional risks of adverse events related to axicabtagene ciloleucel were seen Findings also suggest efficacy trend with median progression-free survival and durability...

Category: Biotechnology, Clinical Trials, Pharmaceutical
Posted: June 3, 2024

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Merus Presents Interim Data on MCLA-145 Monotherapy and in Combination with Pembrolizumab at the 2024 ASCO Annual Meeting

2 June 2024 -- Utrecht, The Netherlands and Massachusetts, US -- Merus NV, a clinical-stage oncology company developing innovative, full-length multispecific antibodies (Biclonics and Triclonics), today announced updated interim clinical...

Category: Biotechnology, Clinical Trials, Drug Discovery
Posted: June 2, 2024

Uppsalalaan 17 3rd & 4th floor 3584 CT Utrecht The Netherlands

Eisai Showcases Oncology Portfolio and Pipeline at ASCO 2024

23 May 2024 -- Tokyo, Japan -- Eisai Co announced today the presentation of research across multiple types of cancer from its oncology portfolio and pipeline during the 2024 American...

Category: Clinical Trials, Drug Discovery
Posted: May 23, 2024

4-6-10 Koishikawa, Bunkyo-ku, Tokyo 112-8088, Japan

Global oncology trial investigator sites increase by half in five years, finds new Phesi analysis

China flagged as significant contributor to growth, but poor investigator selection is causing trial failures 23 May 2024 -- Massachusetts, US -- Phesi, a leading clinical development analytics company, has...

Category: Biotechnology, Clinical Trials
Posted: May 22, 2024

East Lyme, Connecticut, US

Gilead and Kite Oncology to Highlight Broad and Diverse Oncology Portfolio at ASCO 2024

Non-Small Cell Lung Cancer (NSCLC) Development Program Data to be Presented, Including the phase 3 EVOKE-01 Study Updated Results from phase 2 EDGE-Gastric Study of Fc-Silent Anti-TIGIT Domvanalimab Plus Anti-PD-1...

Category: Clinical Trials, Drug Discovery
Posted: May 7, 2024

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Kite to Present Comparison of Outcomes of Tecartus (brexucabtagene autoleucel) from the Pivotal ZUMA-2 Trial Versus the EBMT Registry of alloSCT Patients in Mantle Cell Lymphoma (MCL) at 50th EBMT 2024

Additional analysis demonstrates cost-effectiveness of axicabtagene ciloleucel versus standard of care as second-line therapy In patients With large B-cell lymphoma In Italy 9 April 2024 -- Stockley Park, UK --...

Category: Biotechnology, Clinical Trials
Posted: April 12, 2024

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NuCana Presents Data at the AACR 2024 Annual Meeting Highlighting the Ability of NUC-7738 to Profoundly Alter Tumour Biology in a Paired Biopsy Clinical Study

NUC-7738 reprogrammes cancer cell lipid metabolism to make tumours less aggressive and promote cancer cell death NUC-7738 alters ribosome biogenesis and the regulation of genes critical for cancer growth and...

Category: Biotechnology, Clinical Trials, Pharmaceutical
Posted: April 10, 2024

https://www.nucana.com/

Bio-Rad Launches First Ultrasensitive Multiplexed Digital PCR Assay for Breast Cancer Mutation Detection in Clinical Research

Highly Sensitive and Multiplexed Assay for the Detection, Discrimination and Quantification of Key Mutations in ESR1 Gene for Breast Cancer, Developed for Bio-Rad’s QX600 Droplet Digital PCR System 2 April...

Category: Clinical Trials
Posted: April 2, 2024

Bio-Rad Laboratories Ltd. The Junction Station Road Watford Hertfordshire WD17 1ET

Nonacus launches test for comprehensive genomic profiling, integrated with bioinformatics and analysis software

2 April 2024 -- Birmingham, UK -- Genetic testing company, Nonacus, has launched GALEAS Tumor, a next generation sequencing (NGS) test that provides comprehensive genomic profiling of tumours, allowing clinicians...

Category: Biotechnology
Posted: April 2, 2024

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